In vitro model alveoli from photodegradable microsphere templates
نویسندگان
چکیده
منابع مشابه
In vitro model alveoli from photodegradable microsphere templates.
Recreating the 3D cyst-like architecture of the alveolar epithelium in vitro has been challenging to achieve in a controlled fashion with primary lung epithelial cells. Here, we demonstrate model alveoli formed within a tunable synthetic biomaterial platform using photodegradable microspheres as templates to create physiologically relevant, cyst structures. Poly(ethylene glycol) (PEG)-based hyd...
متن کاملOrigami model for breathing alveoli.
We previously proposed a morphogenesis-based 4D model of the alveolar structure. However, the model exists only in computer, and is too complicated to be recognized in 2D display. Origami, a Japanese traditional craft, is a 4D object originated from 2D sheet. We introduce origami models approximating our computational alveolar model. One can make, see, and handle the models by oneself. Seeing i...
متن کاملAbsorption from the Pulmonary Alveoli
Experiments upon dogs anesthetized with nembutal and lasting 4 hours, in which the right lymphatic duct and thoracic duct have been cannulated and collection of lung lymph and blood specimens was accomplished after intratracheal instillation of dog plasma, purified bovine serum albumin, crystallized egg albumin, and hemoglobin, have shown that the absorption of such molecules is slight. Experim...
متن کاملIn vitro evaluation of Panax notoginseng Rg1 released from collagen/chitosan-gelatin microsphere scaffolds for angiogenesis
BACKGROUND The emergence of skin substitutes provides a new approach for the treatment of wound repair and healing. The consistent and steady release of angiogenic factors is an important factor in the promotion of angiogenesis in skin substitutes, which usually lack, yet need, a vascular network. METHODS In this study, ginsenoside Rg1, a natural compound isolated from Panax notoginseng (PNS)...
متن کاملPhotodegradable Polyesters for Triggered Release
Photodegradable polyesters were synthesized with a photolabile monomer 2-nitrophenylethylene glycol and dioyl chlorides with different lengths. These polymers can be assembled to form polymeric particles with encapsulation of target substances. Light activation can degrade these particles and release payloads in both aqueous solutions and RAW 264.7 cells.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomaterials Science
سال: 2015
ISSN: 2047-4830,2047-4849
DOI: 10.1039/c5bm00034c